Anti-I17RD/ IL17RD/ HH18 antibody for FACS & in-vivo assay| GMab
Cat:GM-Tg-hg-TA171-Ab
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$3,090.00
SKU
GM-Tg-hg-TA171-Ab
Category Target Antibody
Description
Pre-made anti-IL17RD benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IL17RD mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: IL17RD, gene name: IL17RD, also named as HH18, IL-17RD, IL17RLM, SEF. This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016].
Antigen Information
Catalog No.
GM-Tg-hg-TA171-Ab-1,GM-Tg-hg-TA171-Ab-2
Product Name
Anti-IL17RD monoclonal antibody
Format
mab
Target Name
IL17RD
Gene ID
IL17RD
Gene Name
IL17RD
Gene Alias
HH18, IL-17RD, IL17RLM, SEF
Protein Sub-location
Transmembrane Protein
Category of antibody
FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-IL17RD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.