Anti-NR3L1/ B7-H6/ NCR3LG1 antibody for FACS & in-vivo assay| GMab
Cat:GM-Tg-hg-IO012-Ab
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$3,090.00
SKU
GM-Tg-hg-IO012-Ab
Category Target Antibody
Description
Pre-made anti-B7-H6 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-B7-H6 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: B7-H6, gene name: NCR3LG1, also named as B7-H6, B7H6, DKFZp686O24166. B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011].
Antigen Information
Catalog No.
GM-Tg-hg-IO012-Ab-1,GM-Tg-hg-IO012-Ab-2
Product Name
Anti-B7-H6/NCR3LG1 monoclonal antibody
Format
mab
Target Name
B7-H6
Gene ID
NCR3LG1
Gene Name
NCR3LG1
Gene Alias
B7-H6, B7H6, DKFZp686O24166
Protein Sub-location
Transmembrane Protein
Category of antibody
FACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-B7-H6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.