Anti-IL17B/ IL-17B/ IL-20 functional antibody for cell culture, ELISA & in-vivo assay| GMab
Cat:GM-Tg-hg-IO076-Ab
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$3,090.00
SKU
GM-Tg-hg-IO076-Ab
Category Target Antibody
Description
Pre-made anti-IL17B benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IL17B mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: IL17B, gene name: IL17B, also named as IL-17B, IL-20, NIRF, ZCYTO7. The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015].
Antigen Information
Catalog No.
GM-Tg-hg-IO076-Ab-1,GM-Tg-hg-IO076-Ab-2
Product Name
Anti-IL17B monoclonal antibody
Format
mab
Target Name
IL17B
Gene ID
IL17B
Gene Name
IL17B
Gene Alias
IL-17B, IL-20, NIRF, ZCYTO7
Protein Sub-location
Secreted Protein/Potential Cytokines
Category of antibody
FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-IL17B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.