Norway rat Fmo2 AAV plasmid
Cat:pGMAAV000244
Availability:3-7 business days
Description
Catalog ID
pGMAAV000244
Gene Name
Fmo2
Product Name
Norway rat Fmo2 AAV plasmid
Accession Number
NM_144737.2
Gene ID
246245
Species
Norway rat
Product Type
AAV plasmid
Insert Length
1608
Gene Alias
Predicted to enable N,N-dimethylaniline monooxygenase activity. Predicted to be involved in several processes, including NADPH oxidation; toxin metabolic process; and xenobiotic metabolic process. Predicted to act upstream of or within oxygen metabolic process. Predicted to be located in membrane. Orthologous to human FMO2 (flavin containing dimethylaniline monoxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
Null
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Maker
Regulation
overexpression
