Cat:pGMAD000005
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMAD000005
Gene Name
PKLR
Product Name
Accession Number
NM_000298.5
Gene ID
5313
Species
human
Product Type
Adenovirus plasmid
Insert Length
1725
Gene Alias
PK1;PKL;PKR;PKRL;RPK
Fluorescent Label
NULL
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Maker
NULL
Regulation
overexpression
