Recombinant 2019-nCoV(SARS-CoV-2) Spike Protein RBD T478K mutant (delta variant B.1.617.2 lineage)

Recombinant 2019-nCoV(SARS-CoV-2) Spike Protein RBD T478K mutant (delta variant B.1.617.2 lineage)
The world is in midst of the COVID-19 pandemic. Previously known as B.1.617.2, the variant was first discovered in India in February, where it contributed to a horrific wave of infections which started in the spring: The Economist estimates that there have been more than 1m covid deaths in India this year. The delta variant has spread rapidly across borders, too. According to GISAID, the mutation has been identified in at least 70 countries. The delta variant is the most dangerous SARS-CoV-2 mutation yet.1

Mutations of Spike protein in SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage
Two of the spike mutations are at key residues in the RBD (L452R and T478K), two are in the N-terminal domain (T19R and FR157-158Δ).2

Spike Mutation in SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage Spike-S1 Subunit
N Terminal T19R
FR157-158Δ
Spike-RBD L452R Important residues mutation
T478K Important residues mutation
Spike-S1 Subunit D614G A popular mutation in different new SARS-CoV-2 lineage
Spike-S2 Subunit P681R
D950N
Recombinant 2019-nCoV(SARS-CoV-2) Spike Protein RBD T478K mutant (delta variant B.1.617.2 lineage)

The world is in midst of the COVID-19 pandemic. Previously known as B.1.617.2, the variant was first discovered in India in February, where it contributed to a horrific wave of infections which started in the spring: The Economist estimates that there have been more than 1m covid deaths in India this year. The delta variant has spread rapidly across borders, too. According to GISAID, the mutation has been identified in at least 70 countries. The delta variant is the most dangerous SARS-CoV-2 mutation yet.1

Mutations of Spike protein in SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage
Two of the spike mutations are at key residues in the RBD (L452R and T478K), two are in the N-terminal domain (T19R and FR157-158Δ).2

Spike Mutation in SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage Spike-S1 Subunit
N Terminal T19R
FR157-158Δ
Spike-RBD L452R Important residues mutation
T478K Important residues mutation
Spike-S1 Subunit D614G A popular mutation in different new SARS-CoV-2 lineage
Spike-S2 Subunit P681R
D950N