Cat:GMP-h-CTx
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Product Details

Genemedi produces core diagnostic ingredients for test of Metabolic diseases (osteoporosis) and related syndrome. GeneMedi offers paired diagnostics grade β-isomerized C-terminal telopeptides (β-CTx) antibodies (monoclonal antibody, mab) and antigens for Metabolic diseases (osteoporosis) rapid test kit of β-isomerized C-terminal telopeptides (β-CTx) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Metabolic diseases (osteoporosis ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Bone is a metabolically active tissue, and almost 10% of the adult bone is remodeled every year. Bone remodeling comprises bone resorption and formation. During the remodeling process, the activity of osteoblasts and osteoclasts results in the release of proteins or peptides. The peptide products are either proteins released by the cells, such as bone-specific alkaline phosphatase (BAP) and osteocalcin (OC) or degradation products of cellular activity, such as urinary hydroxyproline, deoxypyridinoline, β-isomerized C-terminal telopeptides (β-CTx), total procollagen type 1 amino-terminal propeptide (tP1NP), etc [14]. The measurement of these clinical biomarkers, categorized as biochemical bone markers, in serum and urine is widely used as a rapid means to monitor cellular activity of bone [15]. β-CTx and other substances that originate during bone resorption are called bone resorption markers, while tP1NP, BAP, and OC, which are generated from bone reconstruction, are called bone formation markers.

Product Description

Cat No. of Pruducts

GMP-h-CTx-Ag01:Recombinant Human ¦Â-CTx Protein

Product Name

Recombinant Human β-CTx Protein

Target

β-isomerized C-terminal telopeptides

Alias of Target/Biomarker

#N/A

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

β-isomerized C-terminal telopeptides (β-CTx) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in β-CTx level test of Metabolic diseases (osteoporosis) and related syndrome evaluation

Tag

His

Products description

Recombinant Human β-CTx Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-CTx-Ab01,GMP-h-CTx-Ab02:Anti-Human ¦Â-CTx mouse monoclonal antibody (mAb)

Product Name

Anti-Human β-CTx mouse monoclonal antibody (mAb)

Target

β-isomerized C-terminal telopeptides (β-CTx)

Alias of Target/Biomarker

#N/A

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human β-isomerized C-terminal telopeptides (β-CTx) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other β-isomerized C-terminal telopeptides (β-CTx) antibodies in β-CTx level test of Metabolic diseases (osteoporosis) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human β-CTx mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other β-isomerized C-terminal telopeptides (β-CTx) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.