AAV-Rh10 vector system (AAV-Rh10 expression system, AAV-Rh10 packaging plasmid system)

GeneMedi’s AAV-Rh10 Vector System (AAV serotype -Rh10 helper-free packaging plasmids system) is including AAV-Rh10 Rep-Cap plamid (AAV-Rh10-RC plasmid, or called AAV-RC-Rh10 plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).

GeneMedi’s AAV expression vectors have been inserted with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi’s AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas-Rh10-gRNA AAV expression vector.

AAV-Rh10 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV-Rh10 capsid protein.

The tissue tropism of AAV-Rh10 vector has been validated in neuron(CNS), lung, liver, heart and muscle, with potential applications in tissue-specific gene therapy.

AAV serotype Rh10 (AAV capsid Rh10) system – Introduction

The tissue tropism of AAV-Rh10 vector has been validated in neuron(CNS), lung, liver, heart and muscle, with potential applications in tissue-specific gene therapy.

Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×10¹² vg/ml
Cells: HEK-293T
MOI: MOI=1×10⁴
Determine assay: 36 hours post infection, immunofluorescence microscopy