Valproate is a commonly used antiepileptic drug for the treatment of epilepsy and seizures. It is safe for use in both adults and children more than three years of age. Valproate toxicity can occur both accidentally and intentionally. Acute valproate overdose usually presents with CNS depression/encephalopathy, electrolyte abnormalities such as hypernatremia, elevated transaminase levels, hyperammonemia, and […]
The pregnancy contains multiple steps that must effectively happen at a precise time and in the precise place. For fertilization, oocytes and sperm cells must experience a series of differentiation and development process. Abnormalities on the placement of embryo in the woman’s uterus, decidualization, placentation and intrauterine embryonic development consequence the onset of pre-eclampsia, miscarriage […]
Full List Download Neuropathy refers to the injury or dysfunction of one or more nerves, which results in numbness, tingling, muscle weakness and discomfort in the nerves affected part. Neuropathies often arise from the hands and feet, sometimes other parts of the body also affected. Peripheral neuropathy refers the injury or dysfunction of the peripheral nerves. […]
Full List Download Liver is an important organ and it is responsible for the metabolism, energy storage, and waste filtering. Liver disease is a generally designates to any condition that affects the liver. These conditions may be because of different reasons, but all these reasons damage the liver and affect its function. Many people with […]
Diabetes mellitus is the most known chronic disorder characterized by hyperglycemia. Diabetes mellitus is classified based on the deficiency of insulin production due to β-cell destruction (type 1) and by increased insulin resistance (type 2). The increasing rate of obesity increased the difficulties to determine the type of diabetes mellitus. The classification of diabetes mellitus […]
Calcium homeostasis depends on the reabsorption of bone by osteoclasts and the development of bone by osteoblasts. Imbalance between these two metabolisms leads to osteoporosis. Osteoporosis is a health condition characterized by low bone density, making them fragile and more risk of bone fracture. Osteoporosis develops gradually over several years and is often diagnosed by the […]
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and […]
Full product list of Fc receptor (FcR) and immunoglobulin GeneMedi provides various Fc receptor (FcR), including FcγRI (CD64), FcγRIIA (CD32a), FcγRIIB (CD32b), FcγRIIC (CD32c), FcγRIIIA (CD16a), FcγRIIIB (CD16b), FcγRIII(CD16), FcγRIV, FcRn, TRIM21, FcRL1, FcRL4, FcRL5, FcαRI (CD89), PolyIgR, Fcα/uR (CD351), FcuR, FcεRI, FcεRII (CD23) in human, Cynomolgus/ Rhesus macaque, or mouse. Historically, these receptors have […]
New and Emerging Respiratory Virus Threats Advisory Group NERVTAG was asked to undertake an evidence review to consider whether chest compressions and defibrillation are associated with an increased risk of transmission of acute respiratory infections. Furthermore, it was asked to give an opinion on whether chest compressions and defibrillation should be considered to be aerosol […]
Published 23 December 2020 Detection of an epidemiological cluster associated with a new variant of concern 1. Working with academic collaborators at the University of Oxford, PHE Porton Down has been evaluating the performance of lateral flow devices (LFDs) since mid-August 2020. Over 60 have been considered to date, approximately 30% of which have progressed to extended evaluation […]
