Pre-made Atoltivimab benchmark antibody ( Whole mAb, anti-Zaire Ebolavirus GP therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Atoltivimab biosimilar, Whole Mab: Anti-Zaire Ebolavirus GP therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Atoltivimab is a Zaire ebolavirus glycoprotein-directed human monoclonal antibody that is part of the fixed-dose combination atoltivimab/maftivimab/odesivimab that is used for the treatment of Zaire ebolavirus (Ebola virus).
| Products Name (INN Index) | Pre-Made Atoltivimab biosimilar, Whole Mab: Anti-Zaire Ebolavirus GP therapeutic antibody |
|---|---|
| INN Name | Atoltivimab |
| Target | Zaire Ebolavirus GP |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2018 |
| Year Recommended | 2019 |
| Companies | Regeneron Pharmaceuticals |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Ebola virus infections |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | Zaire Ebolavirus GP |
| Package |
