Pre-made Bedinvetmab benchmark antibody ( Canine Whole mAb, anti-Canine NGFB therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Bedinvetmab biosimilar, Canine Whole Mab: Anti-Canine NGFB therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Bedinvetmab is a canine monoclonal antibody (mAb) targeting Nerve Growth Factor (NGF). The inhibition of NGF mediated cell signalling has demonstrated to provide relief from pain associated with osteoarthritis. … The presence of binding antibodies to bedinvetmab in dogs was assessed using a multitier approach.
| Products Name (INN Index) | Pre-Made Bedinvetmab biosimilar, Canine Whole Mab: Anti-Canine NGFB therapeutic antibody |
|---|---|
| INN Name | Bedinvetmab |
| Target | Canine NGFB |
| Format | Canine Whole mAb |
| Derivation | Caninized |
| Species Reactivity | Canine |
| CH1 Isotype | IgG2 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2018 |
| Year Recommended | 2019 |
| Companies | NA |
| Conditions Approved | NA |
| Conditions Active | Canine lupus familiaris |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | Canine NGFB |
| Package |
