Pre-made Benralizumab benchmark antibody ( Whole mAb, anti-IL5RA therapeutic antibody, Anti-CD125/CDw125/HSIL5R3/IL5R Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Benralizumab biosimilar, Whole mAb, Anti-IL5RA Antibody: Anti-CD125/CDw125/HSIL5R3/IL5R therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Benralizumab, sold under the brand name Fasenra, is a monoclonal antibody medication which is developed by MedImmune for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).[2][3]
| Products Name (INN Index) | Pre-Made Benralizumab biosimilar, Whole mAb, Anti-IL5RA Antibody: Anti-CD125/CDw125/HSIL5R3/IL5R therapeutic antibody |
|---|---|
| INN Name | Benralizumab |
| Target | IL5RA |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2009 |
| Year Recommended | 2010 |
| Companies | AstraZeneca,Cincinnati Children's Hospital Medical Center,Kyowa Hakko,Kyowa Hakko Kirin,McMaster University,MedImmune,National Jewish Medical and Research Center,BioWa |
| Conditions Approved | Asthma |
| Conditions Active | Chronic obstructive pulmonary disease,Nasal polyps,Atopic dermatitis,Churg-Strauss syndrome,Hypereosinophilic syndrome,Rhinosinusitis,Eosinophilic gastroenteritis |
| Conditions Discontinued | Skin disorders |
| Development Tech | POTELLIGENT Technology |
| Previous Name | NA |
| Gm Offical Target Name | IL5RA |
| Package |
