Pre-made Bezlotoxumab benchmark antibody ( Whole mAb, anti-Toxin A therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infections.
| Products Name (INN Index) | Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody |
|---|---|
| INN Name | Bezlotoxumab |
| Target | Toxin A |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | NFD |
| 100% SI Structure | 4np4:HL:IM |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2012 |
| Year Recommended | 2013 |
| Companies | Medarex,University of Massachusetts Medical School,Merck & Co,Merck Sharp & Dohme |
| Conditions Approved | Clostridium difficile |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | Medarex HuMAb Mouse |
| Previous Name | NA |
| Gm Offical Target Name | Toxin A |
| Package |
