Pre-made Bimekizumab benchmark antibody ( Whole mAb, anti-IL17A/IL17 therapeutic antibody, Anti-CTLA-8/CTLA8A/ILA17 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-070

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SKU GMP-Bios-ab-070 Category Tag

Product Details

Pre-Made Bimekizumab biosimilar, Whole mAb, Anti-IL17A/IL17 Antibody: Anti-CTLA-8/CTLA8A/ILA17 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bimekizumab (INN) is a humanized anti-IL17A and IL-17F monoclonal antibody[2] that is being investigated for ankylosing spondylitis, psoriatic arthritis, and psoriasis.

Products Name (INN Index)

Pre-Made Bimekizumab biosimilar, Whole mAb, Anti-IL17A/IL17 Antibody: Anti-CTLA-8/CTLA8A/ILA17 therapeutic antibody

INN Name

Bimekizumab

Target

IL17A

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2013

Companies

UCB

Conditions Approved

Plaque psoriasis

Conditions Active

Ankylosing spondylitis,Psoriatic arthritis,Hidradenitis suppurativa,Ulcerative colitis,Axial spondylarthritis

Conditions Discontinued

Psoriasis,Rheumatoid arthritis

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

IL17A/IL17

Package

, ,

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