Pre-made Cemiplimab benchmark antibody ( Whole mAb, anti-PDCD1/PD-1 therapeutic antibody, Anti-CD279/PD1/SLEB2/hSLE1 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Cemiplimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cemiplimab, sold under the brand name Libtayo, is a monoclonal antibody medication for the treatment of squamous cell skin cancer. Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway.
| Products Name (INN Index) | Pre-Made Cemiplimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody |
|---|---|
| INN Name | Cemiplimab |
| Target | PDCD1 |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2018 |
| Year Recommended | 2019 |
| Companies | Inovio Pharmaceuticals,ISA Pharmaceuticals,Regeneron Pharmaceuticals,Sanofi,Sidney Kimmel Cancer Center,SillaJen Biotherapeutics,University of Texas M. D. Anderson Cancer Center |
| Conditions Approved | Squamous cell cancer,Basal cell cancer,Non-small cell lung cancer |
| Conditions Active | Cervical cancer,Oropharyngeal cancer,Prostate cancer,Fallopian tube cancer,Glioblastoma,Multiple myeloma,Ovarian cancer,Peritoneal cancer,Solid tumours,Head and neck cancer,Malignant melanoma,Renal c |
| Conditions Discontinued | B-cell lymphoma |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | PDCD1/PD-1 |
| Package |
