Pre-made Eluvixtamab benchmark antibody ( Bispecific scFv, anti-CD33;CD3E therapeutic antibody, Anti-p67/SIGLEC3/SIGLEC-3;T3E/TCRE/IMD18 Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Eluvixtamab biosimilar, Bispecific scFv, Anti-CD33;CD3E Antibody: Anti-p67/SIGLEC3/SIGLEC-3;T3E/TCRE/IMD18 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Eluvixtamab (formerly AMG 330) is a bispecific antibody targeting cell surface markers CD33 and CD3, being developed by Amgen, for the treatment of acute.
| Products Name (INN Index) | Pre-Made Eluvixtamab biosimilar, Bispecific scFv, Anti-CD33;CD3E Antibody: Anti-p67/SIGLEC3/SIGLEC-3;T3E/TCRE/IMD18 therapeutic antibody |
|---|---|
| INN Name | Eluvixtamab |
| Target | CD33,CD3E |
| Format | Bispecific scFv |
| Derivation | Bispecific antibody |
| Species Reactivity | Human |
| CH1 Isotype | na;na |
| VD LC | Kappa,Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2020 |
| Year Recommended | 2021 |
| Companies | Amgen |
| Conditions Approved | NA |
| Conditions Active | Acute myeloid leukaemia |
| Conditions Discontinued | NA |
| Development Tech | BiTE Technology |
| Previous Name | NA |
| Gm Offical Target Name | CD33,CD3E |
| Package |
