Pre-made Guselkumab benchmark antibody ( Whole mAb, anti-IL23A/IL23 therapeutic antibody, Anti-IL23P19/P19/SGRF Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Guselkumab biosimilar, Whole mAb, Anti-IL23A/IL23 Antibody: Anti-IL23P19/P19/SGRF therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Guselkumab, sold under the brand name Tremfya, is a monoclonal antibody against interleukin-23 used for the treatment of plaque psoriasis.
| Products Name (INN Index) | Pre-Made Guselkumab biosimilar, Whole mAb, Anti-IL23A/IL23 Antibody: Anti-IL23P19/P19/SGRF therapeutic antibody |
|---|---|
| INN Name | Guselkumab |
| Target | IL23A |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | 4m6m:HL/4m6n:HL |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2013 |
| Year Recommended | 2014 |
| Companies | Janssen Biotech,MorphoSys,Taiho Pharmaceutical |
| Conditions Approved | Erythrodermic psoriasis,Palmoplantar pustulosis,Plaque psoriasis,Psoriatic arthritis,Pustular psoriasis |
| Conditions Active | Crohn's disease,Hidradenitis suppurativa,Ulcerative colitis,Familial adenomatous polyposis,Psoriasis,Giant cell arteritis,Lupus nephritis,Systemic scleroderma |
| Conditions Discontinued | Rheumatoid arthritis |
| Development Tech | MorphoSys HuCAL Phage Display |
| Previous Name | NA |
| Gm Offical Target Name | IL23A |
| Package |
