Pre-made Izuralimab benchmark antibody ( Bispecific Mixed mAb and scFv, anti-ICOS;PDCD1/PD-1 therapeutic antibody, Anti-AILIM/CD278/CVID1;CD279/SLEB2/hPD-1/hPD-l/hSLE1 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-287

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SKU GMP-Bios-ab-287 Category Tags ,

Product Details

Pre-made Izuralimab benchmark antibody (Bispecific Mixed mAb and scFv, anti-ICOS;PDCD1/PD-1 therapeutic antibody, Anti-AILIM/CD278/CVID1;CD279/SLEB2/hPD-1/hPD-l/hSLE1 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Products Name (INN Index)

Pre-Made Izuralimab biosimilar, Bispecific Mixed mAb and scFv, Anti-ICOS;PDCD1/PD-1 antibody: Anti-AILIM/CD278/CVID1;CD279/SLEB2/hPD-1/hPD-l/hSLE1 therapeutic antibody

INN Name

Izuralimab

Target

ICOS,PDCD1

Format

Bispecific Mixed mAb and scFv

Derivation

Bispecific antibody

Species Reactivity

Human

CH1 Isotype

IgG1;na

VD LC

Kappa,Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Active

100% SI Structure

None;None

99% SI Structure

None;None

95-98% SI Structure

None;None

Year Proposed

2020

Companies

Xencor

Conditions Approved

NA

Conditions Active

Solid tumours

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

ICOS,PDCD1

Package

, ,

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