Pre-made Naxitamab benchmark antibody ( Whole mAb, anti-Ganglioside GD2 therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Naxitamab biosimilar, Whole Mab: Anti-Ganglioside GD2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Naxitamab, sold under the brand name Danyelza, is an anti-cancer medication. It is a monoclonal antibody used in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) for people one year of age and older with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow demonstrating a partial response, minor response, or stable disease to prior therapy.
| Products Name (INN Index) | Pre-Made Naxitamab biosimilar, Whole Mab: Anti-Ganglioside GD2 therapeutic antibody |
|---|---|
| INN Name | Naxitamab |
| Target | Ganglioside GD2 |
| Format | Whole mAb |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Approved |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2018 |
| Year Recommended | 2019 |
| Companies | Memorial Sloan-Kettering Cancer Center,Y-mAbs Therapeutics |
| Conditions Approved | Neuroblastoma |
| Conditions Active | Osteosarcoma |
| Conditions Discontinued | Breast cancer,Sarcoma,Small cell lung cancer |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | Ganglioside GD2 |
| Package |
