Pre-made Oleclumab benchmark antibody ( Whole mAb, anti-NT5E/CD73 therapeutic antibody, Anti-NT/eN/NT5/NTE/eNT/E5NT/CALJA Antibody) for drug discovery and mechanism of action (MOA) research
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
Product Details
Pre-Made Oleclumab biosimilar, Whole mAb, Anti-NT5E/CD73 Antibody: Anti-NT/eN/NT5/NTE/eNT/E5NT/CALJA therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Oleclumab (INN; development code MEDI9447) is a human monoclonal antibody targeting the ectonucleotidase CD73 that was designed for the treatment of pancreatic and colorectal and other cancers.
| Products Name (INN Index) | Pre-Made Oleclumab biosimilar, Whole mAb, Anti-NT5E/CD73 Antibody: Anti-NT/eN/NT5/NTE/eNT/E5NT/CALJA therapeutic antibody |
|---|---|
| INN Name | Oleclumab |
| Target | NT5E |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2016 |
| Year Recommended | 2017 |
| Companies | MedImmune,AstraZeneca,European Network of Gynaecological Oncological Trial Groups,Jules Bordet Institute |
| Conditions Approved | NA |
| Conditions Active | Non-small cell lung cancer,Ovarian cancer,Breast cancer,Pancreatic cancer,Bladder cancer,Solid tumours |
| Conditions Discontinued | Prostate cancer |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | NT5E |
| Package |
