Pre-made Orticumab benchmark antibody ( Whole mAb, anti-OxLDL therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Orticumab biosimilar, Whole Mab: Anti-OxLDL therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Orticumab (INN) is a human monoclonal antibody that is used as an anti-inflammatory agent and binds to oxLDL. It acts as an immunomodulator.
| Products Name (INN Index) | Pre-Made Orticumab biosimilar, Whole Mab: Anti-OxLDL therapeutic antibody |
|---|---|
| INN Name | Orticumab |
| Target | OxLDL |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2012 |
| Year Recommended | 2013 |
| Companies | Abcentra,BioInvent International,Genentech |
| Conditions Approved | NA |
| Conditions Active | Atherosclerosis,Psoriasis |
| Conditions Discontinued | NA |
| Development Tech | Human Phage Display |
| Previous Name | NA |
| Gm Offical Target Name | OxLDL |
| Package |
