Pre-made Ozoralizumab benchmark antibody ( Bispecific Single Domains (VH-VH'-VH), anti-TNFA/TNF;ALB therapeutic antibody, Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-419

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SKU GMP-Bios-ab-419 Category Tags ,

Product Details

Pre-Made Ozoralizumab biosimilar, Bispecific Single Domains (VH-VH’-VH), Anti-TNFA/TNF;ALB Antibody: Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Ozoralizumab is a humanized monoclonal antibody designed for the treatment of inflammatory diseases.

Products Name (INN Index)

Pre-Made Ozoralizumab biosimilar, Bispecific Single Domains (VH-VH'-VH), Anti-TNFA/TNF;ALB Antibody: Anti-DIF/TNF-alpha/TNFSF2/TNLG1F;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody

INN Name

Ozoralizumab

Target

TNFA,ALB

Format

Bispecific Single Domains (VH-VH'-VH)

Derivation

Bispecific antibody

Species Reactivity

Human

CH1 Isotype

NA

VD LC

NA

Highest_Clin_Trial (Jan '20)

Preregistration

Est. Status

Active

100% SI Structure

None;None

99% SI Structure

None;None

95-98% SI Structure

5m2j:D;None

Year Proposed

2011

Companies

Ablynx,Eddingpharm,Pfizer,Taisho Pharmaceutical

Conditions Approved

NA

Conditions Active

Rheumatoid arthritis

Conditions Discontinued

Ankylosing spondylitis,Crohn's disease,Psoriatic arthritis

Development Tech

Nanobody Technology

Previous Name

NA

Gm Offical Target Name

TNFA,ALB

Package

, ,

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