Pre-made Racotumomab benchmark antibody ( Whole mAb, anti-Idiotope of anti-NeuGc-ganliosides therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-463

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SKU GMP-Bios-ab-463 Category Tag

Product Details

Pre-Made Racotumomab biosimilar, Whole Mab: Anti-Idiotope of Anti-NeuGc-ganliosides therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Racotumomab (trade name Vaxira) is a therapeutic cancer vaccine for the treatment of solid tumors that is currently under clinical development by Recombio, an international public-private consortium with the participation of the Center of Molecular Immunology at Havana, Cuba (CIM) and researchers from Buenos Aires University and National University of Quilmes in Argentina. It induces the patient’s immune system to generate a response against a cancer-specific molecular target with the purpose of blocking tumor growth, slowing disease progression and ultimately increasing patient survival.

Products Name (INN Index)

Pre-Made Racotumomab biosimilar, Whole Mab: Anti-Idiotope of Anti-NeuGc-ganliosides therapeutic antibody

INN Name

Racotumomab

Target

Idiotope of anti-NeuGc-ganliosides

Format

Whole mAb

Derivation

Mouse

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2008

Companies

Center of Molecular Immunology,Elea,Innogene Kalbiotech,Recombio

Conditions Approved

Non-small cell lung cancer

Conditions Active

Neuroblastoma

Conditions Discontinued

Breast cancer,Colorectal cancer,Malignant melanoma,Small cell lung cancer,Solid tumours

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

Idiotope of anti-NeuGc-ganliosides

Package

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