Pre-made Rontalizumab benchmark antibody ( Whole mAb, anti-IFNA1 therapeutic antibody, Anti-IFL/IFN3/leIF DD Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-494

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SKU GMP-Bios-ab-494 Category Tag

Product Details

Pre-Made Rontalizumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Rontalizumab is a humanized monoclonal antibody being developed by Genentech. As of November 2009, it is being investigated in a clinical trial for the treatment of systemic lupus erythematosus.¡¢

Products Name (INN Index)

Pre-Made Rontalizumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibody

INN Name

Rontalizumab

Target

IFNA1

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG2

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Discontinued

100% SI Structure

4z5r:WV:BA:UT:SR:KJ:ML:QP:ZY

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2009

Companies

Chugai Pharmaceutical,Genentech

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

Systemic lupus erythematosus

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

IFNA1

Package

, ,

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