Pre-made Simlukafusp benchmark antibody ( Whole mAb Fusion, anti-FAP therapeutic antibody, Anti-FAPA/SIMP/DPPIV/FAPalpha Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Simlukafusp biosimilar, Whole mAb Fusion, Anti-FAP Antibody: Anti-FAPA/SIMP/DPPIV/FAPalpha therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Products Name (INN Index) | Pre-Made Simlukafusp biosimilar, Whole mAb Fusion, Anti-FAP Antibody: Anti-FAPA/SIMP/DPPIV/FAPalpha therapeutic antibody |
|---|---|
| INN Name | Simlukafusp |
| Target | FAP |
| Format | Whole mAb Fusion |
| Derivation | NA |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2019 |
| Year Recommended | 2020 |
| Companies | Roche |
| Conditions Approved | NA |
| Conditions Active | Malignant melanoma,Renal cell carcinoma |
| Conditions Discontinued | Solid tumours |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | FAP |
| Package |
