Pre-made Tosatoxumab benchmark antibody ( Whole mAb, anti-Toxin A therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Tosatoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
osatoxumab is a fully-human monoclonal antibody (IgG1¦Ë) targeting the Staphylococcus aureus alpha-toxin or the S. aureus alpha-hemolysin 1,2,3 and thereby preserving human immune cells by protecting against destruction of host cells mediated by the toxin.
| Products Name (INN Index) | Pre-Made Tosatoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody |
|---|---|
| INN Name | Tosatoxumab |
| Target | Toxin A |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2013 |
| Year Recommended | 2014 |
| Companies | Aridis Pharmaceuticals,Kenta Biotech |
| Conditions Approved | NA |
| Conditions Active | Nosocomial pneumonia |
| Conditions Discontinued | Sepsis |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | Toxin A |
| Package |
