Pre-made Ulocuplumab benchmark antibody ( Whole mAb, anti-CXCR4 therapeutic antibody, Anti-FB22/HM89/LAP3/LCR1/NPYR/WHIM/CD184/LAP-3/LESTR/NPY3R/NPYRL/WHIMS/HSY3RR/NPYY3R/WHIMS1/D2S201E Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Ulocuplumab biosimilar, Whole mAb, Anti-CXCR4 Antibody: Anti-FB22/HM89/LAP3/LCR1/NPYR/WHIM/CD184/LAP-3/LESTR/NPY3R/NPYRL/WHIMS/HSY3RR/NPYY3R/WHIMS1/D2S201E therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Ulocuplumab (INN; development code MDX-1338) is a monoclonal antibody designed for the treatment of hematologic malignancies.
| Products Name (INN Index) | Pre-Made Ulocuplumab biosimilar, Whole mAb, Anti-CXCR4 Antibody: Anti-FB22/HM89/LAP3/LCR1/NPYR/WHIM/CD184/LAP-3/LESTR/NPY3R/NPYRL/WHIMS/HSY3RR/NPYY3R/WHIMS1/D2S201E therapeutic antibody |
|---|---|
| INN Name | Ulocuplumab |
| Target | CXCR4 |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I/II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2013 |
| Year Recommended | 2014 |
| Companies | Bristol-Myers Squibb,Medarex,University of Bari |
| Conditions Approved | NA |
| Conditions Active | Acute myeloid leukaemia,Solid tumours,Waldenstrom's macroglobulinaemia,Neuroectodermal tumours |
| Conditions Discontinued | B-cell lymphoma,B-cell prolymphocytic leukaemia,Precursor cell lymphoblastic leukaemia-lymphoma,Multiple myeloma |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | CXCR4 |
| Package |
