Pre-made Vantictumab benchmark antibody ( Whole mAb, anti-FZD Family therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Vantictumab biosimilar, Whole Mab: Anti-FZD Family therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Vantictumab is a human IgG2 monoclonal antibody designed for the treatment of cancer.
| Products Name (INN Index) | Pre-Made Vantictumab biosimilar, Whole Mab: Anti-FZD Family therapeutic antibody |
|---|---|
| INN Name | Vantictumab |
| Target | FZD Family |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG2 |
| VD LC | Lambda |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2013 |
| Year Recommended | 2014 |
| Companies | Bayer HealthCare Pharmaceuticals,OncoMed Pharmaceuticals |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Breast cancer,Non-small cell lung cancer,Pancreatic cancer |
| Development Tech | MorphoSys HuCAL Phage Display |
| Previous Name | NA |
| Gm Offical Target Name | FZD Family |
| Package |
