Pre-made Vobarilizumab benchmark antibody ( Bispecific Single Domains (VH-VH'), anti-IL6R;ALB therapeutic antibody, Anti-CD126/HIES5/IL-1Ra/IL-6R/IL-6R-1/IL-6RA/IL6Q/IL6QTL/IL6RA/IL6RQ/gp80;FDAHT/HSA/PRO0883/PRO0903/PRO1341 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-625

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SKU GMP-Bios-ab-625 Category Tags ,

Product Details

Pre-Made Vobarilizumab biosimilar, Bispecific Single Domains (VH-VH’), Anti-IL6R;ALB Antibody: Anti-CD126/HIES5/IL-1Ra/IL-6R/IL-6R-1/IL-6RA/IL6Q/IL6QTL/IL6RA/IL6RQ/gp80;FDAHT/HSA/PRO0883/PRO0903/PRO1341 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Vobarilizumab (INN; development code ALX0061) is a humanized monoclonal antibody designed for the treatment of inflammatory autoimmune diseases.

Products Name (INN Index)

Pre-Made Vobarilizumab biosimilar, Bispecific Single Domains (VH-VH'), Anti-IL6R;ALB Antibody: Anti-CD126/HIES5/IL-1Ra/IL-6R/IL-6R-1/IL-6RA/IL6Q/IL6QTL/IL6RA/IL6RQ/gp80;FDAHT/HSA/PRO0883/PRO0903/PRO1

INN Name

Vobarilizumab

Target

IL6R,ALB

Format

Bispecific Single Domains (VH-VH')

Derivation

Bispecific antibody

Species Reactivity

Human

CH1 Isotype

NA

VD LC

NA

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Discontinued

100% SI Structure

None;None

99% SI Structure

None;None

95-98% SI Structure

None;None

Year Proposed

2015

Companies

Ablynx

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

Rheumatoid arthritis,Systemic lupus erythematosus

Development Tech

Nanobody Technology

Previous Name

NA

Gm Offical Target Name

IL6R,ALB

Package

, ,

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