Pre-made Zansecimab benchmark antibody ( Whole mAb, anti-ANGPT2 therapeutic antibody, Anti-AGPT2/ANG2/LMPHM10 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-641

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SKU GMP-Bios-ab-641 Category Tag

Product Details

Pre-Made Zansecimab biosimilar, Whole mAb, Anti-ANGPT2 Antibody: Anti-AGPT2/ANG2/LMPHM10 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Zansecimab (formerly LY 3127804) is a selective monoclonal antibody against angiopoietin 2 (Ang2), being developed by Eli Lilly and Company, for the treatment of solid tumours including gastric cancer and hepatocellular carcinoma (HCC) and COVID-19 pneumonia.

Products Name (INN Index)

Pre-Made Zansecimab biosimilar, Whole mAb, Anti-ANGPT2 Antibody: Anti-AGPT2/ANG2/LMPHM10 therapeutic antibody

INN Name

Zansecimab

Target

ANGPT2

Format

Whole mAb

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG4

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2020

Companies

Eli Lilly

Conditions Approved

NA

Conditions Active

COVID-19

Conditions Discontinued

Solid tumours

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

ANGPT2

Package

, ,

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