Pre-made Zolbetuximab benchmark antibody ( Whole mAb, anti-CLDN18 therapeutic antibody, Anti-SFTA5/SFTPJ Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Zolbetuximab biosimilar, Whole mAb, Anti-CLDN18 Antibody: Anti-SFTA5/SFTPJ therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Zolbetuximab (development code IMAB362) is an experimental monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.[1]
| Products Name (INN Index) | Pre-Made Zolbetuximab biosimilar, Whole mAb, Anti-CLDN18 Antibody: Anti-SFTA5/SFTPJ therapeutic antibody |
|---|---|
| INN Name | Zolbetuximab |
| Target | CLDN18 |
| Format | Whole mAb |
| Derivation | Chimeric (Mouse/Human) |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2017 |
| Year Recommended | 2018 |
| Companies | Ganymed Pharmaceuticals |
| Conditions Approved | NA |
| Conditions Active | Gastric cancer,Oesophageal cancer,Pancreatic cancer |
| Conditions Discontinued | Solid tumours |
| Development Tech | NA |
| Previous Name | Claudiximab |
| Gm Offical Target Name | CLDN18 |
| Package |
