Pre-made Socazolimab benchmark antibody ( Whole mAb, anti-CD274/PD-L1 therapeutic antibody, Anti-B7-H/B7H1/PDCD1L1/PDCD1LG1 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-695

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SKU GMP-Bios-ab-695 Category Tag

Product Details

Pre-Made Socazolimab biosimilar, Whole mAb, Anti-CD274/PD-L1 Antibody: Anti-B7-H/B7H1/PDCD1L1/PDCD1LG1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.Socazolimab (also known as STI A1014, STI 1014) is?a fully human monoclonal antibody targeting the programmed death ligand 1 (PD-L1), being developed by Lees Pharmaceutical

Products Name (INN Index)

Pre-Made Socazolimab biosimilar, Whole mAb, Anti-CD274/PD-L1 Antibody: Anti-B7-H/B7H1/PDCD1L1/PDCD1LG1 therapeutic antibody

INN Name

Socazolimab

Target

CD274

Format

Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

G1

VD LC

Lambda

Highest_Clin_Trial (Jan '20)

Phase-III

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2021

Companies

Sorrento Therapeutics,China Oncology Focus Ltd,Lee's Pharmaceutical

Conditions Approved

NA

Conditions Active

Small cell lung cancer,Oesophageal cancer,Osteosarcoma,Urogenital cancer,Cervical cancer,Malignant melanoma

Conditions Discontinued

Cancer

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

CD274

Package

, ,

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