Pre-made Tecaginlimab benchmark antibody ( Whole mAb, anti-CD40;TNFRSF9/CD137 therapeutic antibody, Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-701

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SKU GMP-Bios-ab-701 Category Tags ,

Product Details

Pre-Made Tecaginlimab biosimilar, Whole mAb, Anti-CD40;TNFRSF9/CD137 Antibody: Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Products Name (INN Index)

Pre-Made Tecaginlimab biosimilar, Whole mAb, Anti-CD40;TNFRSF9/CD137 Antibody: Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 therapeutic antibody

INN Name

Tecaginlimab

Target

CD40,TNFRSF9

Format

Bispecific Whole mAb

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

G1;G1

VD LC

Kappa,Kappa

Highest_Clin_Trial (Jan '20)

Phase-I/II

Est. Status

Active

100% SI Structure

None;None

99% SI Structure

None;None

95-98% SI Structure

None;None

Year Proposed

2021

Companies

Genmab

Conditions Approved

NA

Conditions Active

Solid tumours

Conditions Discontinued

NA

Development Tech

DuoBody

Previous Name

NA

Gm Offical Target Name

CD40,TNFRSF9

Package

, ,

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