Pre-made Albiglutide benchmark antibody (Peptide Protein fusion , anti-GLP1R therapeutic antibody, Anti-GLP-1-R/GLP-1R Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-made Albiglutide benchmark antibody (Peptide Protein fusion , anti-GLP1R therapeutic antibody, Anti-GLP-1-R/GLP-1R Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Albiglutide (trade names Eperzan in Europe and Tanzeum in the US) is a glucagon-like peptide-1 agonist (GLP-1 agonist) drug marketed by GlaxoSmithKline (GSK) for treatment of type 2 diabetes.
As of 217 it is unclear if it affects a person’s risk of death.[1] GSK has announced that it intends to withdraw the drug from the worldwide market by July 218 for economic reasons.
| Products Name (INN Index) | Pre-Made Albiglutide Biosimilar, Peptide Protein Fusion targeting GLP1R: (Glp-1)2 Peptide-Albumin(Alb) Fusion Protein targetingGLP-1-R/GLP-1R |
|---|---|
| INN Name | albiglutide |
| Target | GLP1R |
| Format | Peptide Protein fusion |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | Fusion – (GCG (glucagon) 98-127 (glucagon-like peptide 1, GLP1) 7- 36)2 – ALB (albumin, human serum albumin, HSA) 25-609 |
| VD LC | Fusion – (GCG (glucagon) 98-127 (glucagon-like peptide 1, GLP1) 7- 36)2 – ALB (albumin, human serum albumin, HSA) 25-609 |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | GlaxoSmithKline (Brentford UK) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | GLP1R |
| Package |
