Pre-made Altumomab benchmark antibody (Radiolabelled antibody, anti-CEACAM5/CD66e therapeutic antibody, Anti-CEA Antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-made Altumomab benchmark antibody (Radiolabelled antibody, anti-CEACAM5/CD66e therapeutic antibody, Anti-CEA Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Indium (111In) altumomab pentetate (INN) (USP, indium In 111 altumomab pentetate; trade name Hybri-ceaker) is a mouse monoclonal antibody linked to pentetate which acts as a chelating agent for the radioisotope indium-111. The drug is used for the diagnosis of colorectal cancer.[1][2]
| Products Name (INN Index) | Pre-Made Altumomab Biosimilar, Radiolabelled Antibody, Anti-CEACAM5/CD66e Antibody: Anti-CEA therapeutic antibody |
|---|---|
| INN Name | altumomab |
| Target | CEACAM5 |
| Format | Radiolabelled antibody |
| Derivation | Mus musculus |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 – nd |
| VD LC | IgG1 – nd |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Eli?Lilly (Indianapolis IN USA) / Hybritech Inc. (San Diego CA USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | CEACAM5 |
| Package |
