Pre-made Bectumomab benchmark antibody (Fab Fusion, anti-CD22 therapeutic antibody, Anti-SIGLEC-2/SIGLEC2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-751

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SKU GMP-Bios-INN-751 Category Tag

Product Details

Pre-made Bectumomab benchmark antibody (Fab Fusion, anti-CD22 therapeutic antibody, Anti-SIGLEC-2/SIGLEC2 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bectumomab (marketed under the trade name LymphoScan) is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m. It is used to detect non-Hodgkin’s lymphoma.[1][2]

Products Name (INN Index)

Pre-Made Bectumomab Biosimilar, Fab Fusion, Anti-Cd22 Antibody: Anti-SIGLEC-2/SIGLEC2 therapeutic antibody

INN Name

bectumomab

Target

CD22

Format

Fab Fusion

Derivation

Mus musculus

Species Reactivity

Human

CH1 Isotype

Fab' – G2a – kappa

VD LC

Fab' – G2a – kappa

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

Immunomedics?Inc. (Morris Plains NJ USA)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

CD22

Package

, ,

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