Pre-Made Efaprinermin Alfa Biosimilar, Fusion Protein targeting TNFRSF18 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AITR/CD357/ENERGEN/GITR/GITR-D for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Efaprinermin Alfa Biosimilar, Fusion Protein targeting TNFRSF18 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AITR/CD357/ENERGEN/GITR/GITR-D is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Efaprinermin Alfa contains tumor necrosis factor superfamily protein TNFSF18 (human) trimer fusion protein with immunoglobulin g1 (human fc fragment). It is used for the high-value therapeutic targets for inflammatory or immune modulation in autoimmune diseases, transplant recipients, or cancers.
| Products Name (INN Index) | Pre-Made Efaprinermin Alfa Biosimilar, Fusion Protein targeting TNFRSF18 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AITR/CD357/ENERGEN/GITR/GITR-D |
|---|---|
| INN Name | efaprinermin alfa |
| Target | TNFRSF18 |
| Format | Fusion Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | Fusion – [TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2 – IGHG1 Fc (Fragment constant) |
| VD LC | Fusion – [TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2 – IGHG1 Fc (Fragment constant) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | OncoMed Pharmaceuticals (Redwood City CA USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | TNFRSF18 |
| Package |
