Pre-made Exbivirumab benchmark antibody (Whole mAb, anti-HBV (hepatitis B virus) surface antigen (HBsAg) [Hepatitis B virus] therapeutic antibody) for drug discovery and mechanism of action (MOA) research
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Product Details
Anti-HBV (hepatitis B virus) surface antigen (HBsAg) [Hepatitis B virus] therapeutic antibody (Pre-made Exbivirumab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Exbivirumab is a human monoclonal antibody[1] developed for the treatment of hepatitis B infections.[2]
| Products Name (INN Index) | Pre-Made Exbivirumab Biosimilar, Whole Mab: Anti-Hbv (Hepatitis B Virus) Surface Antigen (Hbsag) [Hepatitis B Virus] therapeutic antibody |
|---|---|
| INN Name | exbivirumab |
| Target | HBV (hepatitis B virus) surface antigen (HBsAg) [Hepatitis B virus] |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 – lambda |
| VD LC | IgG1 – lambda |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Cubist Pharmaceuticals, Inc. (Lexington MA USA) / XTL Biopharmaceuticals (Herzliya Israel) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | HBV (hepatitis B virus) surface antigen (HBsAg) [Hepatitis B virus] |
| Package |
