Pre-Made Glucagon Biosimilar, Recombinant Protein targeting GCGR: Recombinant therapeutic protein targeting GGR/GL-R/MVAH for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Glucagon Biosimilar, Recombinant Protein targeting GCGR: Recombinant therapeutic protein targeting GGR/GL-R/MVAH is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises concentration of glucose and fatty acids in the bloodstream, and is considered to be the main catabolic hormone of the body. It is also used as a medication to treat a number of health conditions. Its effect is opposite to that of insulin, which lowers extracellular glucose. It is produced from proglucagon, encoded by the GCG gene.
| Products Name (INN Index) | Pre-Made Glucagon Biosimilar, Recombinant Protein targeting GCGR: Recombinant therapeutic protein targeting GGR/GL-R/MVAH |
|---|---|
| INN Name | glucagon |
| Target | Gcgr |
| Format | Recombinant Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | GCG (glucagon) 1- 29 |
| VD LC | GCG (glucagon) 1- 29 |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Eli?Lilly (Indianapolis IN USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | GCGR |
| Package |
