Pre-Made Insulin Efsitora Alfa Biosimilar, Fusion Protein targeting INSR fused with human IGHG2 Fc (Fragment constant): Recombinant therapeutic protein targeting CD220/HHF5 for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Insulin Efsitora Alfa Biosimilar, Fusion Protein targeting INSR fused with human IGHG2 Fc (Fragment constant): Recombinant therapeutic protein targeting CD220/HHF5 is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Insulin Efsitora Alfa is a human insulin B-chain fused via a G2SG4 peptide linker to human insulin A-chain variant and a peptide linker to a human immunoglobulin G2 Fc fragment. It is used as an antidiabetic drug.
| Products Name (INN Index) | Pre-Made Insulin Efsitora Alfa Biosimilar, Fusion Protein targeting INSR fused with human IGHG2 Fc (Fragment constant): Recombinant therapeutic protein targeting CD220/HHF5 |
|---|---|
| INN Name | insulin efsitora alfa |
| Target | INSR |
| Format | Fusion Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | Fusion – INS (insulin, IDDM1, IDDM2, "insulin- dependent diabetes mellitus 2") – IGHG2 Fc (Fragment constant) |
| VD LC | Fusion – INS (insulin, IDDM1, IDDM2, "insulin- dependent diabetes mellitus 2") – IGHG2 Fc (Fragment constant) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Eli?Lilly (Indianapolis IN USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | INSR |
| Package |
