Pre-Made Lorukafusp Alfa biosimilar, Fusion Protein: Recombinant therapeutic protein targeting ganglioside GD2 fused with human IL2 (interleukin 2, IL-2) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-898

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SKU GMP-Bios-INN-898 Category Tag

Product Details

Pre-Made Lorukafusp Alfa biosimilar, Fusion Protein: Recombinant therapeutic protein targeting ganglioside GD2 fused with human IL2 (interleukin 2, IL-2) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Lorukafusp Alfa is a fusion protein comprised of a monoclonal antibody targeting the GD2 disialoganglioside linked to interleukin-2, which may inhibit growth and induce an immune response against GD2-expressing tumors

Products Name (INN Index)

Pre-Made Lorukafusp Alfa biosimilar, Fusion Protein: Recombinant therapeutic protein targeting ganglioside GD2 fused with human IL2 (interleukin 2, IL-2)

INN Name

lorukafusp alfa

Target

Ganglioside GD2

Format

Fusion Protein

Derivation

Chimeric

Species Reactivity

Human

CH1 Isotype

IgG1 – kappa

VD LC

IgG1 – kappa

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

APEIRON?Biologics AG (Vienna Austria)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

Ganglioside GD2

Package

, ,

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