Pre-Made Onercept Biosimilar, Recombinant Protein targeting TNF: Recombinant therapeutic protein targeting DIF/TNFSF2/TNLG1F for drug discovery and mechanism of action (MOA) research
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Product Details
Pre-Made Onercept Biosimilar, Recombinant Protein targeting TNF: Recombinant therapeutic protein targeting DIF/TNFSF2/TNLG1F is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Tumor necrosis factor (TNF) is a proinflammatory cytokine that plays a pivotal part in the pathogenesis of Crohn¡¯s disease (CD). Anti-TNF therapies have been developed for the treatment of CD. Onercept is a recombinant human soluble p55 tumor necrosis factor binding protein for the potential treatment of a number of disorders, including Crohn’s disease, psoriasis and psoriatic arthritis.
| Products Name (INN Index) | Pre-Made Onercept Biosimilar, Recombinant Protein targeting TNF: Recombinant therapeutic protein targeting DIF/TNFSF2/TNLG1F |
|---|---|
| INN Name | onercept |
| Target | TNF |
| Format | Recombinant Protein |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | TNFRSF1A (tumor necrosis factor receptor (TNFR) superfamilly member 1A, TNFAR, TNF-RI, TNF-R-I, p55, CD120a) soluble form (TNF- binding protein 1) |
| VD LC | TNFRSF1A (tumor necrosis factor receptor (TNFR) superfamilly member 1A, TNFAR, TNF-RI, TNF-R-I, p55, CD120a) soluble form (TNF- binding protein 1) |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | NA |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | TNF |
| Package |
