Category Archives: aav

AAV-LC3 production service for Autophagy Flux Detection

customized AAV production Customize Option Autophagy Flux detection vector GM-AAVPAU01: AAV-CMV-mRFP-GFP-LC3GM-AAVPAU02: AAV-CMV-GFP-LC3 AAV Packaging Serotype AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant (AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro, AAV-PHP.B, AAV-PHP.eB, AAV-PHPS, […]

Viral Vector System For gene transduction

Introduction to Virus Packaging System Plasmids Hgher titer and easier purification process with GeneMedi’s viral vector systems for gene transduction. The gene transduction system including AAV system, adenovirus system and lentivirus system. AAV vector system (AAV expression system, AAV packaging plasmid system)-Introduction GeneMedi’s AAV Vector System, also named AAV expression system or AAV packaging plasmid […]

AAV Helper plasmid (AAV adenovirus helper plasmid) map, sequence and production service

AAV Helper Plasmid AAV protocol Download AAV User Manual Download AAV Helper Plasmid – Introduction GeneMedi offer ready-to-use AAV helper plasmid that is optimized for recombinant Adeno-associated virus (rAAV) packaging, production, and manufacturing within the adenovirus (Adv) helper virus-free system. The GeneMedi AAV helper plasmid vector contains a mini adenovirus genome that is necessary for […]

AAV Rep-Cap plasmids (serotypes-specific AAV RC plasmids)

AAV protocol Download AAV User Manual Download AAV Rep-Cap plasmids (serotypes-specific AAV RC plasmids) – Introduction GeneMedi’s AAV Rep-Cap plasmids (serotype-specific AAV RC plasmids), also named AAV-RC plasmid, or AAV-RC plasmid, is part of AAV Vector System. You can produce AAV paticle in 293T cell line in high titer using GeneMedi’s AAV Rep-Cap plasmid with […]

AAV vector system (AAV expression system, AAV packaging plasmid system )

AAV protocol Download AAV User Manual Download Introduction to AAV Vector System (AAV packaging and expression system) GeneMedi’s AAV Vector System (AAV helper-free packaging system) including AAV expression vectors, AAV helper plasmid, and kinds of AAV Rep-Cap plamids (AAV-RC) with different serotypes of AAV capsids containing AAV2, AAV5, AAV6, AAV8, AAV9, AAV-PHP.B, AAV-PHP.eB, AAV PHP.s, […]

AAV FAQs

How can I choose the optimal AAV serotypes for my in vivo study? Genemedi has launched a comprehensive AAV production service. More than 12 AAV serotypes and a variety of capsid engineered AAV vectors are available for targeting different tissues and organs. Different AAV serotypes have different tissue tropism in vivo, the common serotypes and […]

Publication-AAV

Selected Publications using Genemed’s AAV Products/Services Publications Link to the article Products/Services H. Zhu, et. al, ‘Moderate Uv Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain’, Cell, 173 (2018), 1716-27 e17 http://www.ncbi.nlm.nih.gov/pubmed/29779945 AAV virus H. Yang et. al, ‘Laterodorsal Tegmentum Interneuron Subtypes Oppositely Regulate Olfactory Cue-Induced Innate Fear’, […]

Viral vector-based vaccines: AAV vector-based vaccines

COVID-19 vaccine development protocol: PSV Based Neutralization Assay Viral vector-based vaccines Viral vector-based vaccines are vaccines that can deliver specific antigen gene to target cells based on the infection ability of viruses, produce antigens via the nutrition substances in host cells, and then provoke immune responses with the newly synthesized antigens. Compared with the traditional […]

What is Adeno-associated virus (AAV) vector?

AAV protocol Download Adeno Associated Virus (AAV) Adeno-associated virus (AAV) is a small-single strand DNA virus, member of human parvovirus, originally described in the 1960s by Bob Atchison at Pittsburgh and Wallace Rowe at NIH as a contaminant in preparation of adenovirus [1,2]. Shortly after its discovery, AAV was then isolated from humans, but serological studies […]