Pre-made anti-FSCN1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
Cat:GM-Tg-hg-IP0081-Ab
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$3,090.00
SKU
GM-Tg-hg-IP0081-Ab
Category Target Antibody
Description
Pre-made anti-FSCN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FSCN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: FSCN1, gene name: FSCN1, also named as FAN1, HSN, SNL, p55. This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin’s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].
Antigen Information
Catalog No.
GM-Tg-hg-IP0081-Ab-1,GM-Tg-hg-IP0081-Ab-2
Product Name
Anti-FSCN1 monoclonal antibody
Format
mab
Target Name
FSCN1
Gene ID
FSCN1
Gene Name
FSCN1
Gene Alias
FAN1, HSN, SNL, p55
Protein Sub-location
Introcelluar Protein
Category of antibody
Therapeutics Target antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Tag
Fc
Products description
Pre-made anti-FSCN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.