Anti-SMO/ SMO D473H/ CRJS antibody for FACS & in-vivo assay| GMab

Cat:GM-Tg-hg-T16215-Ab
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$3,090.00

SKU GM-Tg-hg-T16215-Ab Category

Description

Pre-made anti-SMO D473H benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SMO D473H mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: SMO D473H, gene name: SMO, also named as CRJS, FZD11, GxH, SMO. The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010].

Antigen Information

Catalog No.

GM-Tg-hg-T16215-Ab-1,GM-Tg-hg-T16215-Ab-2

Product Name

Anti-SMO D473H/SMO monoclonal antibody

Format

mab

Target Name

SMO D473H

Gene ID

SMO

Gene Name

SMO

Gene Alias

CRJS, FZD11, GxH, SMO

Protein Sub-location

Transmembrane Protein

Category of antibody

FACS/Biofunctional Antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-SMO D473H benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.