Anti-PAFA/ PLA2G7/ LDL-PLA2 functional antibody for cell culture, ELISA & in-vivo assay| GMab

Cat:GM-Tg-hg-T69912-Ab
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$3,090.00

SKU GM-Tg-hg-T69912-Ab Category

Description

Pre-made anti-PLA2G7 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PLA2G7 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: PLA2G7, gene name: PLA2G7, also named as LDL-PLA2, LP-PLA2, PAFAD, PAFAH. The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009].

Antigen Information

Catalog No.

GM-Tg-hg-T69912-Ab-1,GM-Tg-hg-T69912-Ab-2

Product Name

Anti-PLA2G7 monoclonal antibody

Format

mab

Target Name

PLA2G7

Gene ID

PLA2G7

Gene Name

PLA2G7

Gene Alias

LDL-PLA2, LP-PLA2, PAFAD, PAFAH

Protein Sub-location

Secreted Protein/Potential Cytokines

Category of antibody

FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-PLA2G7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.