Cat:GMP-h-B2M
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Product Details

Genemedi produces core diagnostic ingredients for test of Kidney function (renal damages) (renal disease) and related syndrome. GeneMedi offers paired diagnostics grade Beta-2 microglobulin (B2M) antibodies (monoclonal antibody, mab) and antigens for Kidney function (renal damages) (renal disease) rapid test kit of Beta-2 microglobulin (B2M) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Kidney function (renal damages) (renal disease ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.What is Beta-2 microglobulin (B2M) test? Beta-2 microglobulin (B2M) is a protein that is found on the surface of nucleated cells (contain a nucleus) and functions as part of the immune system. This protein is routinely shed by cells into the blood and is present in most body fluids, with highest levels in the blood, generally lower levels in spinal fluid, and trace levels in urine. In the kidneys, B2M passes through blood-filtering units called the glomeruli and is then reabsorbed by the renal proximal tubules, structures that reclaim water, proteins, vitamins, minerals, and other vital substances. Normally, only small amounts of B2M are present in the urine, but when the renal tubules become damaged or diseased, B2M concentrations increase due to the decreased ability to reabsorb this protein. When the glomeruli in the kidneys are damaged, they are unable to filter out B2M, so the level in the blood rises.

Product Description

Cat No. of Pruducts

GMP-h-B2M-Ag01:Recombinant Human B2M Protein

Product Name

Recombinant Human B2M Protein

Target

Beta-2 microglobulin

Alias of Target/Biomarker

IMD43

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation

Tag

His

Products description

Recombinant Human B2M Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-B2M-Ab01,GMP-h-B2M-Ab02:Anti-Human B2M mouse monoclonal antibody (mAb)

Product Name

Anti-Human B2M mouse monoclonal antibody (mAb)

Target

Beta-2 microglobulin (B2M)

Alias of Target/Biomarker

IMD43

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human Beta-2 microglobulin (B2M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Beta-2 microglobulin (B2M) antibodies in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human B2M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Beta-2 microglobulin (B2M) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.