Cat:GMP-h-CA50
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Product Details

Genemedi produces core diagnostic ingredients for test of Cancer (pancreatic and colorectal cancer) and related syndrome. GeneMedi offers paired diagnostics grade Carbohydrate Antigen 50 (CA50) antibodies (monoclonal antibody, mab) and antigens for Cancer (pancreatic and colorectal cancer) rapid test kit of Carbohydrate Antigen 50 (CA50) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cancer (pancreatic and colorectal cancer ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Cancer-associated carbohydrate antigen 50 (CA50) is a ganglioside glycoprotein and is a biomarker for the diagnosis and prognosis of gastrointestinal malignancies, especially of pancreatic and colorectal cancers. The expression level of CA50 has been measured for pancreatic and colorectal cancers and also for other cancers such as breast, lung, renal, prostatic, and ovarian cancers. In addition, it can distinguish the patients of benign disease of atrophic gastritis, pancreatitis, ulcerative colitis, pneumonia, cirrhosis, and autoimmune diseases from healthy persons.

Product Description

Cat No. of Pruducts

GMP-h-CA50-Ag01:Recombinant Human CA50 Protein

Product Name

Recombinant Human CA50 Protein

Target

Carbohydrate Antigen 50

Alias of Target/Biomarker

#N/A

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

Carbohydrate Antigen 50 (CA50) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CA50 level test of Cancer (pancreatic and colorectal cancer) and related syndrome evaluation

Tag

His

Products description

Recombinant Human CA50 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-CA50-Ab01,GMP-h-CA50-Ab02:Anti-Human CA50 mouse monoclonal antibody (mAb)

Product Name

Anti-Human CA50 mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

#N/A

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human Carbohydrate Antigen 50 (CA50) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Carbohydrate Antigen 50 (CA50) antibodies in CA50 level test of Cancer (pancreatic and colorectal cancer) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human CA50 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Carbohydrate Antigen 50 (CA50) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.