Cat:GMP-h-CBL
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Product Details

Genemedi produces core diagnostic ingredients for test of Metabolic diseases (ectopia lentis, learning difficulties and skeletal abnormalities) and related syndrome. GeneMedi offers paired diagnostics grade cystathionine-β-synthase enzyme (CBL) antibodies (monoclonal antibody, mab) and antigens for Metabolic diseases (ectopia lentis, learning difficulties and skeletal abnormalities) rapid test kit of cystathionine-β-synthase enzyme (CBL) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Metabolic diseases (ectopia lentis, learning difficulties and skeletal abnormalities ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Cystathionine beta-synthase (CBS) is the first enzyme in the transsulfuration pathway, catalyzing the conversion of serine and homocysteine to cystathionine and water. Cystathionine beta-synthase (CBS) deficiency is a rare inherited disorder in the methionine catabolic pathway, in which the impaired synthesis of cystathionine leads to accumulation of homocysteine. Severely affected patients usually present in childhood with ectopia lentis, learning difficulties and skeletal abnormalities.

Product Description

Cat No. of Pruducts

GMP-h-CBL-Ag01:Recombinant Human CBL Protein

Product Name

Recombinant Human CBL Protein

Target

cystathionine-β-synthase enzyme

Alias of Target/Biomarker

C-CBL, CBL2, FRA11B, NSLL, RNF55

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

cystathionine-β-synthase enzyme (CBL) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CBL level test of Metabolic diseases (ectopia lentis, learning difficulties and skeletal abnormalities) and related syndrome evaluation

Tag

His

Products description

Recombinant Human CBL Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-CBL-Ab01,GMP-h-CBL-Ab02:Anti-Human CBL mouse monoclonal antibody (mAb)

Product Name

Anti-Human CBL mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

C-CBL, CBL2, FRA11B, NSLL, RNF55

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human cystathionine-β-synthase enzyme (CBL) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other cystathionine-β-synthase enzyme (CBL) antibodies in CBL level test of Metabolic diseases (ectopia lentis, learning difficulties and skeletal abnormalities) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human CBL mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other cystathionine-β-synthase enzyme (CBL) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.