Cat:GMP-h-GDF-15
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Product Details

Genemedi produces core diagnostic ingredients for test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome. GeneMedi offers paired diagnostics grade Growth differentiation factor-15 (GDF-15) antibodies (monoclonal antibody, mab) and antigens for Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) rapid test kit of Growth differentiation factor-15 (GDF-15) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Growth and differentiation factor 15 (GDF-15), previously known as macrophage inhibitory cytokine 1 (MIC-1), is a divergent transforming growth factor β (TGF-β) family member historically associated with cancer cachexia, cardiovascular disease, and a host of other diseases with inflammatory etiologies. GDF-15 is expressed in most tissues only at very low levels, the only human organ that expresses high levels of GDF-15 in healthy conditions is the placenta. However, GDF-15 could be markedly increased in the case of cardiovascular injury, such as pressure overload, myocardial infarction, heart failure, and atherosclerosis.

Product Description

Cat No. of Pruducts

GMP-h-GDF-15-Ag01:Recombinant Human GDF-15 Protein

Product Name

Recombinant Human GDF-15 Protein

Target

Growth differentiation factor-15

Alias of Target/Biomarker

GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

Growth differentiation factor-15 (GDF-15) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation

Tag

His

Products description

Recombinant Human GDF-15 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-GDF-15-Ab01,GMP-h-GDF-15-Ab02:Anti-Human GDF-15 mouse monoclonal antibody (mAb)

Product Name

Anti-Human GDF-15 mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human Growth differentiation factor-15 (GDF-15) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Growth differentiation factor-15 (GDF-15) antibodies in GDF-15 level test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human GDF-15 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Growth differentiation factor-15 (GDF-15) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.